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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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ABI3
ABI family, member 3
ABI3 is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants.
| Gene Name: | ABI family, member 3 |
| Synonyms: | ABI3, ABI gene family member 3, ABI family, member 3, ABI gene family, member 3, New molecule including SH3, SSH3BP3, NESH |
| Target Sequences: | NM_016428 NP_057512.1 Q9P2A4 |
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