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ABR is a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.
Gene Name: | active BCR-related |
Synonyms: | ABR, Active BCR-related, Active BCR-related gene, MDB |
Target Sequences: | NM_021962 NP_068781.2 Q12979 |
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