ACADL

acyl-CoA dehydrogenase, long chain

Long-chain acyl-coA dehydrogenase (ACADL), also abbreviated as LCAD, is a mitochondrial metrix enzyme involved in catalyzing the first reaction in the mitochondrial beta-oxidation cycles for fatty acids. Two other acyl-coA dehydrogenases are also involved in fatty acid oxidation, medium chain and short chain ALDs. However, of these ACADL catalyzes the first and critical step in this process. ACADL is a homotetrameic enzyme of 45-kD. It is synthesized in the cytoplasm a a precursor then processed and targeted to the mitochondria. Genetic deficiency of ACADL is associated with severe hypoglycemia, skeletal muscle weakness, hepatomegaly and cardiomegaly, which can be fatal.

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Proteins (3)

Type

Recombinant (3)

Target

ACADL (3)

Publications

No (3)

Tag

GST (1)

His (1)

His-T7, N-terminus (1)

Species

Human (3)

Source

E. coli (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human ACADL Protein (Recombinant His-T7, N-terminus) (Ile214-Lys430) - LS-G133282

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

28.3kDa

Price:

10 µg/$270; 50 µg/$372; 200 µg/$742; 100 µg/$592; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966

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Human ACADL Protein (Recombinant His) - LS-G1499

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human ACADL Protein (Recombinant GST) (Full Length) - LS-G27320

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.04 kDa

Price:

10 µg/$479; 25 µg/$670

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