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ACCN3 / ASIC3
acid-sensing (proton-gated) ion channel 3
ACCN3 / ASIC3 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
| Gene Name: | acid-sensing (proton-gated) ion channel 3 |
| Family/Subfamily: | Ion Channel , Sodium channel - amiloride-sensitive |
| Synonyms: | ASIC3, Acid-sensing ion channel 3, Acid-sensing ion channel, ACCN3, HASIC3, HTNaC1, Modulatory subunit of ASIC2a, SLNAC1, DRASIC, Testis sodium channel 1, TNaC1 |
| Target Sequences: | NM_020321 NP_064717.1 Q9UHC3 |
Publications (1)
1
Endomorphins potentiate acid-sensing ion channel currents and enhance the lactic acid-mediated increase in arterial blood pressure: effects amplified in hindlimb ischaemia. Mohamed Farrag, Julie K Drobish, Henry L Puhl, Joyce S Kim, Paul B Herold, Marc P Kaufman, Victor Ruiz-Velasco. The Journal of physiology. 2017 December;595:7167-7183. [Full Text Article]
[PubMed:29044528]
[PMC:PMC5709321]
Related Antibodies: LS-C313073.
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Antibodies
(24)
Type
Primary
(24)
Target
ACCN3 / ASIC3
(24)
Reactivity
Human
(19)
Mouse
(7)
Rat
(10)
Bovine
(3)
Chimpanzee
(3)
Dog
(3)
Guinea pig
(3)
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(3)
Monkey
(1)
Rabbit
(3)
Application
IHC
(10)
IHC-P
(5)
WB
(22)
ELISA
(12)
ICC
(1)
Host
rabbit
(21)
guinea pig
(1)
rabbit-new zealand white
(2)
Isotype
IgG
(19)
Clonality
polyclonal pc
(24)
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APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(2)
FITC Conjugated
(2)
HRP Conjugated
(2)
PE Conjugated
(1)
Unconjugated
(16)
Epitope
aa55-83
(7)
aa53-102
(4)
C-Terminus
(2)
191-240 aa, Internal
(1)
aa2-50
(1)
aa285-304
(1)
aa50-100
(1)
aa500-531
(1)
aa56-73
(1)
aa60-95
(1)
Publications
No
(23)
Yes
(1)
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa53-102) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa53-102) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa53-102) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa53-102) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
ACCN3 / ASIC3 Rabbit anti-Rat Polyclonal (aa50-100) Antibody
Mouse, Rat
IHC, WB
Unconjugated
500 µg/$393
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa56-73) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa500-531) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$393
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ACCN3 / ASIC3 Rabbit-New Zealand White anti-Human Polyclonal (aa2-50) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
ACCN3 / ASIC3 Rabbit-New Zealand White anti-Human Polyclonal (aa60-95) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (191-240 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ACCN3 / ASIC3 Guinea pig anti-Rat Polyclonal (aa285-304) Antibody
Rat
ICC, IHC
Unconjugated
50 µl/$529; 150 µl/$901
ACCN3 / ASIC3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
100 µg/$832
ACCN3 / ASIC3 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
100 µl/$801
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal (aa55-83) Antibody
Human
WB
Unconjugated
400 µl/$393
ACCN3 / ASIC3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
20 µl/$275; 100 µl/$389
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product results
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