ACD / PTOP

adrenocortical dysplasia homolog (mouse)

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.

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Products

ELISA Kits (6)

Type

Sandwich (6)

Target

ACD / PTOP (6)

Reactivity

Human (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

96-Well Strip Plate (6)

Publications

No (6)

Sample Type

Plasma (1)

Serum (1)

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Human ACD / PTOP (Sandwich ELISA) ELISA Kit - LS-F39510

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Chicken ACD / PTOP (Sandwich ELISA) ELISA Kit - LS-F40866

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey ACD / PTOP (Sandwich ELISA) ELISA Kit - LS-F40867

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig ACD / PTOP (Sandwich ELISA) ELISA Kit - LS-F40868

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine ACD / PTOP (Sandwich ELISA) ELISA Kit - LS-F40869

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit ACD / PTOP (Sandwich ELISA) ELISA Kit - LS-F40870

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.25 - 80 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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