ACD / PTOP

adrenocortical dysplasia homolog (mouse)

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.

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Products

Proteins (12)

Type

Over-Expression Lysate (6)

Recombinant (6)

Target

ACD / PTOP (12)

Publications

No (12)

Tag

GST (1)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (8)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human ACD / PTOP Protein (Recombinant GST) (Full Length) - LS-G35081

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

85.58 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ACD / PTOP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84028

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.7 kDa

Price:

20 µg/$215

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Human ACD / PTOP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84029

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.6 kDa

Price:

20 µg/$150

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Human ACD / PTOP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84030

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.2 kDa

Price:

20 µg/$215

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ACD / PTOP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101841

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.2 kDa

Price:

100 µg/$710

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Human ACD / PTOP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69189

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.6 kDa

Price:

20 µg/$1,107

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Human ACD / PTOP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69190

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.2 kDa

Price:

20 µg/$1,107

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ACD / PTOP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119771

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.6 kDa

Price:

100 µg/$494

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ACD / PTOP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119772

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.7 kDa

Price:

100 µg/$710

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Human ACD / PTOP Protein (Recombinant His, N-Terminal) (Glu244-Pro432) - LS-G133099

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

23.0kDa

Price:

10 µg/$263; 50 µg/$343; 200 µg/$662; 100 µg/$530; 1 mg/$1,657; 500 µg/$1,242; 5 mg/$2,600; 2 mg/$1,832

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Mouse ACD / PTOP Protein (Recombinant His-T7) (aa21-175) - LS-G24736

Source:

E. coli

Tag:

His-T7

Molecular Weight:

20.6 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Rat ACD / PTOP Protein (Recombinant His-T7) (aa147-342) - LS-G24737

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.6 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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