ACE2 / ACE-2

angiotensin I converting enzyme 2

Angiotensin-Converting Enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function. ACE2 is also the attachment receptor for HCoV-N63, SARS-CoV and SARS-CoV-2. The S1 portion of the coronavirus spike protein attaches to ACE2 presented on the host cell surface. The SARS-CoV-2 virus targets pneumocytes and macrophages expressing ACE2 in the lung, and it is believed to infect ACE2-positive cells in other tissues including the gastrointestinal tract and potentially the liver (in cholangiocytes).

☰ Filters

Products

Proteins (21)

Type

Recombinant (21)

Target

ACE2 / ACE-2 (21)

Product Group

Coronavirus Antibodies Proteins cDNAs (13)

SARS-CoV-2 Associated Proteins (13)

Publications

No (21)

Tag

10His, C-terminus (2)

6His, C-terminus (6)

AVI-6His, C-terminus (1)

Fc, C-terminus (2)

Fc/His,C-terminus (1)

His (2)

His, N-terminus (1)

His-T7 (2)

Human IgG1 Fc, C-terminus (1)

mFc, C-terminus (1)

Mouse IgG Fc, C-terminus (1)

Mouse IgG1 Fc, C-terminus (1)

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Species

Coronavirus SARS-CoV-2 (1)

Human (12)

Mouse (4)

Rat (2)

Rhesus monkey (2)

Source

Baculovirus (1)

E. coli (3)

HEK 293 Cells (2)

Human (3)

Human Cells (9)

Human Embryonic Kidney 293 Cells (2)

Mammalian Cells (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (18)

Biologically Active

Biologically active (8)

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Human ACE2 / ACE-2 Protein (Recombinant Mouse IgG1 Fc, C-terminus) (Met1-Ser740) - LS-G97116

Source:

Human Cells

Tag:

Mouse IgG1 Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110 kDa

Price:

20 µg/$685; 100 µg/$1,523

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Rat ACE2 / ACE-2 Protein (Recombinant His-T7) (aa392-739) - LS-G14417

Source:

E. coli

Tag:

His-T7

Molecular Weight:

43.8 kDa

Price:

50 µg/$480; 10 µg/$287; 200 µg/$957; 100 µg/$767; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278

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Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) - LS-G136815

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.63 kDa

Price:

1 mg/$2,837; 500 µg/$1,987; 50 µg/$698; 10 µg/$356

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Human ACE2 / ACE-2 Protein (Recombinant Human IgG1 Fc, C-terminus) (Met1-Ser740) - LS-G97114

Source:

Human Cells

Tag:

Human IgG1 Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110.3 kDa

Price:

20 µg/$685; 100 µg/$1,485

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Mouse ACE2 / ACE-2 Protein (Recombinant His-T7) (aa93-464) - LS-G14416

Source:

E. coli

Tag:

His-T7

Molecular Weight:

46.6 kDa

Price:

50 µg/$460; 10 µg/$284; 200 µg/$917; 100 µg/$735; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) (Gln18-Ser740) - LS-G38929

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.63kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Mouse ACE2 / ACE-2 Protein (Recombinant His) (Met1-Thr740) - LS-G98691

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85 kDa

Price:

20 µg/$684; 100 µg/$1,485

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Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) (Gln18-Ser740) - LS-G140043

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.6 kDa

Price:

10 µg/$344; 50 µg/$584

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Human ACE2 / ACE-2 Protein (Recombinant Fc, C-terminus) (Gln18-Ser740) - LS-G145894

Source:

Human Cells

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110.5 kDa

Price:

10 µg/$304; 50 µg/$491

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Human ACE2 / ACE-2 Protein (Recombinant mFc, C-terminus) (Gln18-Ser740) - LS-G145896

Source:

Human Cells

Tag:

mFc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110 kDa

Price:

10 µg/$304; 50 µg/$491

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Human ACE2 / ACE-2 Protein (Recombinant AVI-6His, C-terminus) (Gln18-Ser740) - LS-G145897

Source:

Human Cells

Tag:

AVI-6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

86.2 kDa

Price:

20 µg/$416; 100 µg/$910

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Coronavirus SARS-CoV-2 ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) - LS-G145926

Source:

HEK 293 Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.63 kDa

Price:

100 µg/$489; 1 mg/$2,783

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Human ACE2 / ACE-2 Protein (Recombinant His, N-terminus) - LS-G146215

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

16.7kDa

Price:

50 µg/$343; 100 µg/$403

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Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) - LS-G146337

Source:

Baculovirus

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85.1 kDa

Price:

20 µg/$600; 100 µg/$1,603

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Mouse ACE2 / ACE-2 Protein (Recombinant 10His, C-terminus) - LS-G146278

Source:

Human

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.9 kDa

Price:

10 µg/$351; 50 µg/$690

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Rhesus monkey ACE2 / ACE-2 Protein (Recombinant Fc, C-terminus) - LS-G146328

Source:

Human

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110.6 kDa

Price:

10 µg/$351; 50 µg/$690

Select

Rhesus monkey ACE2 / ACE-2 Protein (Recombinant 10His, C-terminus) - LS-G146327

Source:

Human

Tag:

10His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85.1 kDa

Price:

10 µg/$351; 50 µg/$690

Select

Human ACE2 / ACE-2 Protein (Recombinant 6His, C-terminus) - LS-G146504

Source:

Human Embryonic Kidney 293 Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85.1 kDa

Price:

20 µg/$721; 100 µg/$1,603

Select

Human ACE2 / ACE-2 Protein (Recombinant Mouse IgG Fc, C-terminus) - LS-G146509

Source:

Human Embryonic Kidney 293 Cells

Tag:

Mouse IgG Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110 kDa

Price:

20 µg/$685; 1 mg/$5,903

Select

Mouse ACE2 / ACE-2 Protein (Recombinant Fc/His,C-terminus) (Met1-Thr740) - LS-G138451

Source:

HEK 293 Cells

Tag:

Fc/His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

112 kDa

Price:

20 µg/$684; 100 µg/$1,485

Select

Rat ACE2 / ACE-2 Protein (Recombinant His) (Met1-Thr740) - LS-G98310

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85 kDa

Price:

20 µg/$684; 100 µg/$1,485

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