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Acetyl-CoA Carboxylase / ACC

acetyl-CoA carboxylase alpha

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Gene Name: acetyl-CoA carboxylase alpha
Synonyms: ACACA, ACAC, ACC1, ACACAD, ACCA, ACC, ACC-alpha, Acetyl-CoA Carboxylase, Acetyl-CoA carboxylase 1, Acetyl-CoA carboxylase alpha
Target Sequences: Q13085 Q13085

Publications (2)

1
Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin. Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Ge G, Spooner E, Hug C, Gimeno R, Lodish HF. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2009 23:241-58. (WB) [PubMed:18787108] [PMC:PMC2626616]
2
Effects of atypical antipsychotics and haloperidol on PC12 cells: only aripiprazole phosphorylates AMP-activated protein kinase. Takami G, Ota M, Nakashima A, Kaneko YS, Mori K, Nagatsu T, Ota A. Journal of neural transmission (Vienna, Austria : 1996). 2010 117:1139-53. (WB; Rat) [PubMed:20686905] Related Antibodies: LS-C11718.

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Products
ELISA Kits (16)
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Competitive EIA (3)
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Acetyl-CoA Carboxylase / ACC (16)
Human (6)
Mouse (5)
Rat (5)
Bovine (1)
Chicken (1)
96-Well Microplate (1)
96-Well Strip Plate (15)
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Adherent Cell Cultures (1)
Cell Lysates (1)
Plasma (11)
Serum (11)
Tissue Homogenates (4)
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$798
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$750
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Bovine
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Acetyl-CoA Carboxylase / ACC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
Acetyl-CoA Carboxylase / ACC ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).