ACLY / ATP Citrate Lyase

ATP citrate lyase

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ACLY / ATP Citrate Lyase (5)

Publications

No (5)

Tag

6His-SUMO, N-terminus (1)

His,N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Insect Cells (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human ACLY / ATP Citrate Lyase Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65022

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.7 kDa

Price:

20 µg/$1,107

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Human ACLY / ATP Citrate Lyase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74656

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.7 kDa

Price:

20 µg/$150

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ACLY / ATP Citrate Lyase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118774

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.7 kDa

Price:

100 µg/$494

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Human ACLY / ATP Citrate Lyase Protein (Recombinant 6His-SUMO, N-terminus) (aa4-265) - LS-G56069

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human ACLY / ATP Citrate Lyase Protein (Recombinant His,N-terminus) (Met1-Met1101) - LS-G140822

Source:

Insect Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

123 kDa

Price:

50 µg/$1,007

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