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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
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ACOT13 / THEM2
acyl-CoA thioesterase 13
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis.
| Gene Name: | acyl-CoA thioesterase 13 |
| Synonyms: | ACOT13, Acyl-CoA thioesterase 13, HT012, PNAS-27, Hypothalamus protein HT012, THEM2 |
| Target Sequences: | NM_018473 NP_060943.1 Q9NPJ3 |
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