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ACOT8

acyl-CoA thioesterase 8

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.

Gene Name: acyl-CoA thioesterase 8
Synonyms: ACOT8, Acyl-CoA thioesterase 8, Acyl-coenzyme A thioesterase 8, ACTEIII, HNAACTE, HACTE-III, HACTEIII, PTE-1, Thioesterase II, Palmitoyl-CoA hydrolase, PTE1, Choloyl-CoA hydrolase, HTE, PTE-2, PTE2, Thioesterase III
Target Sequences: NM_005469 NP_005460.2 O14734

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
ACOT8 (8)
No (8)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (2)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ACOT8 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
ACOT8 Protein - 12.5% SDS-PAGE of human ACOT8 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.3 kDa
10 µg/$479; 25 µg/$670
ACOT8 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ACOT8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.7 kDa
20 µg/$150
ACOT8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
28.1 kDa
20 µg/$150
ACOT8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.1 kDa
100 µg/$494
ACOT8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.7 kDa
100 µg/$494
ACOT8 Protein
Select
E. coli
His, N-Terminal
35.7 kDa
50 µg/$419
Viewing 1-8 of 8 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).