ACP2 / Acid Phosphatase 2

acid phosphatase 2, lysosomal

ACP2 / Acid Phosphatase 2 encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. LAP-deficiencies in mice cause multiple defects including bone structure alterations, lysosomal storage defects in the kidneys and central nervous system, and an increased tendency towards seizures. An enzymatically-inactive allele of LAP in mice exhibited a more severe phenotype than the null allele, and defects included cerebellum abnormalities, growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

ACP2 / Acid Phosphatase 2 (6)

Publications

No (6)

Tag

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human ACP2 / Acid Phosphatase 2 Protein (Recombinant His) - LS-G3170

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human ACP2 / Acid Phosphatase 2 Protein (Recombinant GST) (Full Length) - LS-G27371

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.27 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ACP2 / Acid Phosphatase 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77154

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.2 kDa

Price:

20 µg/$150

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Human ACP2 / Acid Phosphatase 2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66197

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.1 kDa

Price:

20 µg/$1,107

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ACP2 / Acid Phosphatase 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125220

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.2 kDa

Price:

100 µg/$494

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Human ACP2 / Acid Phosphatase 2 Protein (Recombinant His, N-Terminal) (Tyr40-Ala250) - LS-G132951

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

23.2kDa

Price:

10 µg/$281; 50 µg/$442; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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