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Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C4 to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro). Functions as GTP-dependent lipoate-activating enzyme that generates the substrate for lipoyltransferase.
Gene Name: | acyl-CoA synthetase medium-chain family member 1 |
Synonyms: | ACSM1, Butyrate CoA ligase, Butyrate--CoA ligase 1, LAE, Lipoate-activating enzyme, BUCS1, MACS1 |
Target Sequences: | NM_052956 NP_443188.2 Q08AH1 |
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