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ACTA1 / Skeletal Muscle Actin

Actin, Alpha 1, Skeletal Muscle

Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Gene Name: Actin, Alpha 1, Skeletal Muscle
Synonyms: ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, ASMA, NEM3
Target Sequences: NM_001100 NP_001091.1 P68133

Publications (2)

1
How Different Stocking Densities Affect Growth and Stress Status of Acipenser baerii Early Stage Larvae. Lucia Aidos, Alessandra Cafiso, Valentina Serra, Mauro Vasconi, Daniela Bertotto, Chiara Bazzocchi, Giuseppe Radaelli, Alessia Di Giancamillo. Animals: an open access journal from MDPI. 2020 July;10: [Full Text Article] [PubMed:32731504] [PMC:PMC7460203] Related Antibodies: LS-B4203.
2
TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway. Nariaki Miyao, Yukiko Hata, Hironori Izumi, Ryo Nagaoka, Yuko Oku, Ichiro Takasaki, Taisuke Ishikawa, Shinya Takarada, Mako Okabe, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Tomoyuki Yoshida, Hideyuki Hasegawa, Naomasa Makita, Naoki Nishida, Hisashi Mori, Fukiko Ichida, Keiichi Hirono. PloS one. 2020 Apr;15:e0227393. [Full Text Article] [PubMed:32236096] [PMC:PMC7112173] Related Antibodies: LS-C413476.

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ACTA1 / Skeletal Muscle Actin (11)
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ACTA1 / Skeletal Muscle Actin ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$715
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
ACTA1 / Skeletal Muscle Actin ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
ACTA1 / Skeletal Muscle Actin ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
ACTA1 / Skeletal Muscle Actin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).