ACTL7A

actin-like 7A

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ACTL7A (4)

Publications

No (4)

Tag

GST (1)

His-SUMO (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ACTL7A Protein (Recombinant GST) (Full Length) - LS-G32374

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ACTL7A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89539

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.5 kDa

Price:

20 µg/$150

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ACTL7A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115153

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.5 kDa

Price:

100 µg/$494

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Human ACTL7A Protein (Recombinant His-SUMO) (Full Length) - LS-G22029

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

64.6 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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