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6737 Mowry Ave
Newark, CA 94560
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ACTR8

ARP8 Actin-related Protein 8 Homolog (yeast)

Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.

Gene Name: ARP8 Actin-related Protein 8 Homolog (yeast)
Synonyms: ACTR8, Actin-related protein 8, ARP8, INO80 complex subunit N, INO80N, HArp8
Target Sequences: NM_022899 NP_075050.3 Q9H981

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Proteins (2)
Recombinant (2)
ACTR8 (2)
No (2)
6His, N-terminus (2)
Human (2)
E. coli (2)
Low endotoxin level (2)
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.1kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.1 kDa
10 µg/$317; 50 µg/$524
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).