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ACVRL1

activin A receptor type II-like 1

Activin A receptor, type II-like 1 (also called activin receptor-like kinase 1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The protein (sometimes termed ALK1) shares similar domain structures with 3 other closely related ALK proteins (ALK2, ALK3, and ALK4) that together form a subfamily of receptor serine/threonine kinases. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 deficiency causes hemorrhagic telangiectasia type 2 (HHT2; MIM 600376) also known as Rendu-Osler-Weber syndrome 2 (ORW2).

Gene Name: activin A receptor type II-like 1
Family/Subfamily: Protein Kinase , Activin/TGFb
Synonyms: ACVRL1, ALK1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, HHT, HHT2, SKR3, TSR-I, ORW2
Target Sequences: NM_000020 NP_000011.2 P37023

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Products
ELISA Kits (9)
Cell-Based (1)
Custom (3)
Sandwich (5)
ACVRL1 (9)
Human (5)
Mouse (4)
Rat (2)
96-Well Microplate (1)
96-Well Strip Plate (8)
No (9)
Adherent Cell Cultures (1)
Cell Culture Supernatants (4)
Cell Lysates (3)
Plasma (4)
Serum (4)
Tissue Homogenates (1)
ACVRL1 ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ACVRL1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
ACVRL1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
ACVRL1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$699
ACVRL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$699
ACVRL1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
46.9 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
ACVRL1 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
ACVRL1 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
ACVRL1 ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).