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Vector Laboratories, Inc.
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ADAM15

ADAM metallopeptidase domain 15

Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.

Gene Name: ADAM metallopeptidase domain 15
Family/Subfamily: Protease , Metallopeptidase M12B
Synonyms: ADAM15, ADAM 15, MDC15, Metargidin, MDC-15, TMDC VI
Target Sequences: NM_003815 NP_003806.3 Q13444

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ELISA Kits (3)
Sandwich (3)
ADAM15 (3)
Human (3)
96-Well Strip Plate (3)
No (3)
Cell Culture Supernatants (2)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (1)
ADAM15 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
ADAM15 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
ADAM15 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$901
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).