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ADCY1 / Adenylate Cyclase 1

adenylate cyclase 1 (brain)

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.

Gene Name: adenylate cyclase 1 (brain)
Family/Subfamily: Adenylate cyclase , not assigned-Adenylate cyclase
Synonyms: ADCY1, 3,5-cyclic AMP synthetase, Adenylate cyclase type I, AC1, Adenylate cyclase type 1, Adenylyl cyclase 1, ATP pyrophosphate-lyase 1, Adenyl cyclase, Adenylate cyclase 1 (brain), Adenylate cyclase, type i, ATP pyrophosphate-lyase
Target Sequences: L05500 AAA02907.1 Q08828

Publications (1)

1
Amplified fluorogenic immunoassay for early diagnosis and monitoring of Alzheimer's disease from tear fluid. Sojeong Lee, Eunjung Kim, Chae-Eun Moon, Chaewon Park, Jong-Woo Lim, Minseok Baek, Moo-Kwang Shin, Jisun Ki, Hanna Cho, Yong Woo Ji, Seungjoo Haam. Nature communications. 2023 December;14:8153. [Full Text Article] [PubMed:38071202] [PMC:PMC10710446]

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
ADCY1 / Adenylate Cyclase 1 (4)
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His, N-Terminal (1)
His-T7 (1)
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293T Cells (1)
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HEK 293 Cells (1)
ADCY1 / Adenylate Cyclase 1 Protein - Recombinant Adenylate Cyclase 1, Brain By SDS-PAGE
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E. coli
His, N-Terminal
34.0 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
ADCY1 / Adenylate Cyclase 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
123.3 kDa
20 µg/$215
ADCY1 / Adenylate Cyclase 1 Protein - Recombinant Adenylate Cyclase 1, Brain By SDS-PAGE
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E. coli
His-T7
29.4 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
ADCY1 / Adenylate Cyclase 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
123.3 kDa
100 µg/$710
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).