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ADCY3 / Adenylate Cyclase 3

Adenylate Cyclase 3

ADCY3 / Adenylate Cyclase 3 is adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.

Gene Name: Adenylate Cyclase 3
Family/Subfamily: Adenylate cyclase , not assigned-Adenylate cyclase
Synonyms: ADCY3, AC-III, AcIII, Adenylyl cyclase 3, AC3, Adenylate cyclase type III, ATP pyrophosphate-lyase 3, Adenylate cyclase 3, Adenylate cyclase type 3, Adenylyl cyclase, type III, KIAA0511
Target Sequences: NM_004036 NP_004027.2 O60266

Publications (2)

1
Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling. Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay. Developmental cell. 2020 September;54:710-726e8. [Full Text Article] [PubMed:32702291] [PMC:PMC9042708] Related Antibodies: LS-C204505.
2
Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E. Skylar I Dewees, Romana Vargová, Katherine R Hardin, Rachel E Turn, Saroja Devi, Joshua Linnert, Uwe Wolfrum, Tamara Caspary, Marek Eliáš, Richard A Kahn. Molecular biology of the cell. 2022 April;33:ar33. [Full Text Article] [PubMed:35196065] [PMC:PMC9250359] Related Antibodies: LS-C204505.

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Proteins (4)
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Recombinant (2)
ADCY3 / Adenylate Cyclase 3 (4)
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GST, N-terminus (1)
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ADCY3 / Adenylate Cyclase 3 Protein - Recombinant Adenylate Cyclase 3 By SDS-PAGE
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E. coli
His-T7
30.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$3,361
ADCY3 / Adenylate Cyclase 3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ADCY3 / Adenylate Cyclase 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
128.8 kDa
100 µg/$710
ADCY3 / Adenylate Cyclase 3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
128.8 kDa
20 µg/$215
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).