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ADGRB1 / BAI1
brain-specific angiogenesis inhibitor 1
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas
| Gene Name: | brain-specific angiogenesis inhibitor 1 |
| Family/Subfamily: | GPCR , Orphan-B |
| Synonyms: | ADGRB1, BAI1, GDAIF |
| Target Sequences: | NM_001702 BAA23647.1 O14514 |
Publications (1)
1
Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame. Shohei Wakao, Yo Oguma, Yoshihiro Kushida, Yasumasa Kuroda, Kazuki Tatsumi, Mari Dezawa. Cellular and molecular life sciences : CMLS. 2022 October;79:542. [Full Text Article]
[PubMed:36203068]
[PMC:PMC9537123]
Related Antibodies: LS-C177193.
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ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rat, Hamster, Mouse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bovine, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (aa691-740) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (Gln732) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (aa60-350) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (670-750 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (aa683-732) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
IHC
Unconjugated
400 µl/$393
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Fast Shipping
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human, Monkey
ICC, IF, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
200 µl/$952
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
ADGRB1 / BAI1 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$393
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
0.1 ml/$386
ADGRB1 / BAI1 Rabbit anti-Human Polyclonal (C-Terminus) (DY550) Antibody
Mouse, Human
IHC, IHC-P
DY550 Conjugated
0.1 ml/$416
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