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ADGRE1 / EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
ADGRE1 / EMR1 / F4/80 is a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | egf-like module containing, mucin-like, hormone receptor-like 1 |
| Family/Subfamily: | GPCR , Orphan-B |
| Synonyms: | ADGRE1, EMR1 hormone receptor, F4/80, EGF-like module receptor 1, TM7LN3, EMR1 |
| Target Sequences: | NM_001974 NP_001965.3 Q14246 |
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