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ADGRL2 / LPHN2

latrophilin 2

Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covalently linked as a heterodimer.

Gene Name: latrophilin 2
Family/Subfamily: GPCR , Orphan-B
Synonyms: ADGRL2, Cl2aa, CIRL2, CL2, Latrophilin 1, Latrophilin-2, Lectomedin-1, Latrophilin 2, Latrophilin homolog 2 (cow), KIAA0786, Beta-latrotoxin receptor, CIRL-2, Latrophilin homolog 1, Latrotoxin receptor 2, Latrotoxin receptor homolog 2, LEC1, LPHH1, LPHN2
Target Sequences: NM_012302 NP_036434.1 O95490

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ADGRL2 / LPHN2 (3)
No (3)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (1)
Rat (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
ADGRL2 / LPHN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
157.18 kDa
20 µg/$215
ADGRL2 / LPHN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
157.18 kDa
100 µg/$710
ADGRL2 / LPHN2 Protein - Recombinant  Latrophilin 2 By SDS-PAGE
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E. coli
His-T7
33.7 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).