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ADGRL4 / ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
The ETL protein receptor has been characterized as an Orphan-B GPCR with an unknown ligand. ETL has a large extracellular domain with epidermal growth factor (EGF)-like repeats, a seven-transmembrane domain, and a short cytoplasmic tail. ETL expression is developmentally regulated in heart.
| Gene Name: | EGF, latrophilin and seven transmembrane domain containing 1 |
| Family/Subfamily: | GPCR , Orphan-B |
| Synonyms: | ADGRL4, ELTD1, ETL, ETL protein, KPG_003 |
| Target Sequences: | BC025721 AAH25721.1 Q9HBW9 |
Publications (2)
1
Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion10<sup> Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA12<sup> Present address: AbbVie Bioresearch Center, Worcester, MA, USA14<sup> Department of Anatomy and Neurobiology, University of Puerto Rico, Medical Sciences Campus, PO Box 365067, San Juan, 00936-5067, Puerto Rico. jacqueline.flores@upr.edu. Jonathan Guihurt Santiago , Neikelyn Burgos-Tirado , Daniella Dorta Lafontaine , José C Mendoza Sierra , Roberto Herrera Camacho , Clara M Vecchini Rodríguez , Vanessa Morales-Tirado , Jacqueline Flores-Otero. BMC cancer. 2021 Jan;21:53. [Full Text Article]
[PubMed:33430814]
[PMC:PMC7802354]
Related Antibodies: LS-C379622.
2
ELTD1 Promotes Gastric Cancer Cell Proliferation, Invasion and Epithelial-Mesenchymal Transition Through MAPK/ERK Signaling by Regulating CSK. Bo Sun, Fang-Jing Zhong. International journal of general medicine. 2021 Aug;14:4897-4911. [Full Text Article]
[PubMed:34475781]
[PMC:PMC8407680]
Related Antibodies: LS-B15548.
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Products
ELISA Kits
(3)
Type
Custom
(1)
Sandwich
(2)
Target
ADGRL4 / ELTD1
(3)
Reactivity
Human
(1)
Mouse
(1)
Rat
(1)
Format
96-Well Strip Plate
(3)
Publications
No
(3)
Sample Type
Plasma
(3)
Serum
(3)
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Custom
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
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