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The ETL protein receptor has been characterized as an Orphan-B GPCR with an unknown ligand. ETL has a large extracellular domain with epidermal growth factor (EGF)-like repeats, a seven-transmembrane domain, and a short cytoplasmic tail. ETL expression is developmentally regulated in heart.
Gene Name: | EGF, latrophilin and seven transmembrane domain containing 1 |
Family/Subfamily: | GPCR , Orphan-B |
Synonyms: | ADGRL4, ELTD1, ETL, ETL protein, KPG_003 |
Target Sequences: | BC025721 AAH25721.1 Q9HBW9 |
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