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ADORA2A/Adenosine A2A Receptor

adenosine A2a receptor

ADORA2A/Adenosine A2A Receptor is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.

Gene Name: adenosine A2a receptor
Family/Subfamily: GPCR , Adenosine
Synonyms: ADORA2A, Adenosine receptor A2a, ADORA2, A2a receptor, Adenosine A2a receptor, Adenosine A2 receptor, Adenosine receptor subtype A2a, HA2aR, RDC8, AA2AR, A2AR
Target Sequences: NM_000675 NP_000666.2 P29274

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ADORA2A/Adenosine A2A Receptor (10)
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Dog (1)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (9)
No (10)
Plasma (8)
Serum (8)
Tissue Homogenates (4)
ADORA2A/Adenosine A2A Receptor ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ADORA2A/Adenosine A2A Receptor ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$730
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ADORA2A/Adenosine A2A Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).