ADORA2A/Adenosine A2A Receptor

adenosine A2a receptor

ADORA2A/Adenosine A2A Receptor is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ADORA2A/Adenosine A2A Receptor (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ADORA2A/Adenosine A2A Receptor Protein (Recombinant GST) (Full Length) - LS-G27375

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

71.1 kDa

Price:

2 µg/$439

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Human ADORA2A/Adenosine A2A Receptor Protein (Recombinant GST, N-terminus) (aa147-267) - LS-G57714

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ADORA2A/Adenosine A2A Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99107

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.5 kDa

Price:

100 µg/$494

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Human ADORA2A/Adenosine A2A Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74318

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.5 kDa

Price:

20 µg/$150

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