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ADPRH / ARH1 catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. Unlike the rat and mouse enzymes that require DTT for maximal activity, the human enzyme is DTT-independent. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Gene Name: | ADP-ribosylarginine hydrolase |
Synonyms: | ADPRH, ADP-ribosylarginine hydrolase, ARH1 |
Target Sequences: | NM_001125 NP_001116.1 P54922 |
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