ADRA2C

adrenoceptor alpha 2C

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

ADRA2C (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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Human ADRA2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74438

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.3 kDa

Price:

20 µg/$215

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ADRA2C Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123044

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.3 kDa

Price:

100 µg/$710

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