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ADRM1 is a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.
Gene Name: | adhesion regulating molecule 1 |
Synonyms: | ADRM1, Adhesion regulating molecule 1, Adhesion-regulating molecule 1, ARM1, gp110, HRpn13, Rpn13 homolog, M(r) 110,000 surface antigen, ARM-1, Rpn13 |
Target Sequences: | NM_007002 NP_008933.2 Q16186 |
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