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AEN

apoptosis enhancing nuclease

Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.

Gene Name: apoptosis enhancing nuclease
Synonyms: AEN, Apoptosis enhancing nuclease, Apoptosis-enhancing nuclease, ISG20L1, Pp12744
Target Sequences: NM_022767 NP_073604.3 Q8WTP8

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
AEN (4)
No (4)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
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293T Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$150
AEN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
36.2 kDa
100 µg/$494
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HEK 293 Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$1,107
AEN Protein
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E. coli
His-SUMO
40.08 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).