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AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
Gene Name: | AFG3-like AAA ATPase 2 |
Family/Subfamily: | Protease , Metallopeptidase M41 |
Synonyms: | AFG3L2, AFG3-like protein 2, SPAX5, Spinocerebellar ataxia 28, Paraplegin-like protein, ATPase family gene 3, yeast, SCA28 |
Target Sequences: | NM_006796 NP_006787.2 Q9Y4W6 |
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