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AGMO / TMEM195 is a tetrahydrobiopterin- and iron-dependent enzyme that cleaves the ether bond of alkylglycerols. Sequence comparisons distinguish this protein as forming a third, distinct class of tetrahydrobiopterin-dependent enzymes. Variations in this gene have been associated with decreased glucose-stimulated insulin response, type 2 diabetes, and susceptibility to intracranial aneurysms.
Gene Name: | alkylglycerol monooxygenase |
Synonyms: | AGMO, Alkylglycerol monooxygenase, Glyceryl-ether monooxygenase, TMEM195, Transmembrane protein 195 |
Target Sequences: | Q6ZNB7 Q6ZNB7 |
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