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6737 Mowry Ave
Newark, CA 94560
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AGT / Angiotensinogen
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone.Angiotensin-3: stimulates aldosterone release.Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.
| Gene Name: | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| Family/Subfamily: | Hormone , not assigned-Hormone |
| Synonyms: | AGT, ANHU, Angiotensinogen, Pre-angiotensinogen, SERPINA8, Serpin A8 |
| Target Sequences: | NM_000029 NP_000020.1 P01019 |
Publications (6)
1
Reduced expression of angiotensin II and angiotensin receptor type 1 and type 2 in resistance arteries from nasal lesions in granulomatosis with polyangiitis (Wegener's granulomatosis). Dimitrijevic I, Rissler P, Luts L, Edvinsson L. Scandinavian journal of rheumatology. 2011 40:448-52. (ICC, IHC; Human)
[PubMed:21936613]
2
Partial restoration of cardio-vascular defects in a rescued severe model of spinal muscular atrophy. Shababi M, Habibi J, Ma L, Glascock JJ, Sowers JR, Lorson CL. Journal of molecular and cellular cardiology. 2012 52:1074-82. (WB; Mouse)
[PubMed:22285962]
[PMC:PMC3327806]
3
Improved Assay for Quantifying a Redox Form of Angiotensinogen as a Biomarker for Pre-Eclampsia: A Case-Control Study. Rahgozar S, Amirian T, Qi M, Shahshahan Z, Entezar-E-Ghaem M, Ghasemi Tehrani H, Miroliaei M, Krilis SA, Giannakopoulos B. PloS one. 2015 10:e0135905. (WB; Human)
[Full Text Article]
[PubMed:26312482]
[PMC:PMC4552422]
Related Antibodies: LS-C80597.
☰ Filters
Products
Proteins
(21)
Type
Over-Expression Cell Culture Supernatant
(1)
Over-Expression Lysate
(3)
Recombinant
(17)
Target
AGT / Angiotensinogen
(21)
Publications
No
(21)
Tag
6His, C-terminus
(2)
6His, N-terminus
(1)
6His-SUMO, N-terminus
(1)
8His, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(2)
His, N-Terminal
(4)
His,C-terminus
(1)
His-GST
(1)
His-S
(2)
Myc-DDK (Flag)
(3)
Species
Human
(14)
Mouse
(3)
Rat
(3)
Source
293F Cells
(2)
293T Cells
(1)
E. coli
(6)
HEK 293 Cells
(6)
Human Cells
(2)
Mammalian Cells
(1)
Wheat Germ Extract
(3)
Purification
Purified
(7)
Low Endotoxin Level
Low endotoxin level
(4)
E. coli
His-S
56.1 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
E. coli
His-GST
76.7 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
E. coli
His-S
55.3 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
E. coli
His
24.5 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.7kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
HEK 293 Cells
Myc-DDK (Flag)
49.7 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
53.11 kDa
100 µg/$494
HEK 293 Cells
His, N-Terminal
~53 kDa (55-65 kDa reducing conditions)
10 µg/$289; 200 µg/$646; 50 µg/$360
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
100 µg/$843
293T Cells
Myc-DDK (Flag)
53.11 kDa
20 µg/$150
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.7 kDa
10 µg/$344; 50 µg/$584
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
50.8 kDa
100 µg/$721
293F Cells
His, N-Terminal
60kDa
10 µg/$277; 50 µg/$417; 200 µg/$832; 100 µg/$665; 1 mg/$1,920; 500 µg/$1,468; 5 mg/$2,905; 2 mg/$2,105
293F Cells
His, N-Terminal
65kDa
10 µg/$276; 50 µg/$410; 200 µg/$820; 100 µg/$655; 1 mg/$1,902; 500 µg/$1,452; 5 mg/$2,864; 2 mg/$2,087
Wheat Germ Extract
GST
79.09 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST
77 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
8His, N-terminus
52.1 kDa
100 µg/$298
HEK 293 Cells
6His, N-terminus
52.1 kDa
200 µl/$283
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His, N-Terminal
52 kDa
10 µg/$265; 100 µg/$365; 250 µg/$518; 50 µg/$315
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product results
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