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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
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AGTR2 / AT2 Receptor
angiotensin II receptor, type 2
Type 2 Angiotensin Receptor (AT2) has been suggested to affect development, cell differentiation, apoptosis, and regeneration in various tissues. AT2 receptor has been shown to exert counteracting effects on cellular growth and differentiation, vascular tone, and the release of arginine vasopressin (AVP). In each condition, the AT2 receptor appears to down-modulate actions mediated by the AT1 receptor, resulting in decreased cellular proliferation, decreased levels of serum AVP levels, or decreased vasoconstrictor responses. Binding of angiotensin II to the AT2 receptor inhibits guanylate cyclase. Recently, AT2 receptor has been suggested to affect brain development and cognitive function (Vervoort et al. 2002).
| Gene Name: | angiotensin II receptor, type 2 |
| Family/Subfamily: | GPCR , Angiotensin |
| Synonyms: | AGTR2, Angiotensin ii receptor type 2, Angiotensin II type-2 receptor, AT2 receptor, AT2, At2r, MRX88, Angiotensin ii at2, Angiotensin receptor 2, Type-2 angiotensin II receptor, ATGR2 |
| Target Sequences: | NM_000686 NP_000677.2 P50052 |
Publications (2)
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