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AHRR / AhR Repressor

aryl-hydrocarbon receptor repressor

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Gene Name: aryl-hydrocarbon receptor repressor
Synonyms: AHRR, AhR repressor, AHH, AHHR, BHLHe77, Dioxin receptor repressor, KIAA1234
Target Sequences: AB033060 BAA86548.1 A9YTQ3

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Proteins (2)
Recombinant (2)
AHRR / AhR Repressor (2)
No (2)
GST, N-terminus (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
Purified (1)
AHRR / AhR Repressor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
AHRR / AhR Repressor Protein - Recombinant Aryl Hydrocarbon Receptor Repressor (AHRR) by SDS-PAGE
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E. coli
None
50.4kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).