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AIF1 / IBA1

allograft inflammatory factor 1

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Gene Name: allograft inflammatory factor 1
Synonyms: AIF1, AIF-1, Em:AF129756.17, G1, IRT-1, Protein G1, IBA1, IRT1
Target Sequences: NM_004847 NP_004838.1 P55008

Publications (6)

1
Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide. Wu LP, Ahmadvand D, Su J, Hall A, Tan X, Farhangrazi ZS, Moghimi SM. Nature communications. 2019 October;10:4635. [Full Text Article] [PubMed:31604928] [PMC:PMC6789111]
2
N-docosahexaenoylethanolamine reduces neuroinflammation and cognitive impairment after mild traumatic brain injury in rats. Arina I Ponomarenko, Anna A Tyrtyshnaia, Evgeny A Pislyagin, Inessa V Dyuizen, Ruslan M Sultanov, Igor V Manzhulo. Scientific reports. 2021 January;11:756. [Full Text Article] [PubMed:33436960] [PMC:PMC7804312]
3
Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments. Malabika Maulik , Swarup Mitra , McKenzie Sweeney, Brianna Lu, Barbara E Taylor, Abel Bult-Ito. Journal of functional foods. 2019 Feb;53:306-317. [Full Text Article] [PubMed:31558914] [PMC:PMC6761827]
4
Hippocampal Neurogenesis in Conditions of Chronic Stress Induced by Sciatic Nerve Injury in the Rat. Evgeniia Egorova, Anna Starinets, Anna Tyrtyshnaia, Arina Ponomarenko, Igor Manzhulo. Cells, tissues, organs. 2019 July;207:58-68. [Full Text Article] [PubMed:31284284]
5
Spontaneous neoplasia in captive syngnathid species: A retrospective case series (2003-2014) and literature review. Daniela Denk, Ranieri Verin, Lorenzo Ressel, Eleanor Lewis, Mark F Stidworthy. Journal of fish diseases. 2020 August;43:929-939. [Full Text Article] [PubMed:32557754] Related Antibodies: LS-B2402.
6
Neoplastic pleural effusion and intrathoracic metastasis of a scapular osteosarcoma in a dog: a multidisciplinary integrated diagnostic approach. Luis Mesquita, Jeremy Mortier, Lorenzo Ressel, Riccardo Finotello, Paolo Silvestrini, Martina Piviani. Veterinary clinical pathology. 2017 June;46:337-343. [Full Text Article] [PubMed:28370186] Related Antibodies: LS-B2402.
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Antibodies (114)
Primary (114)
AIF1 / IBA1 (114)
Human (70)
Mouse (40)
Rat (44)
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mouse (36)
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monoclonal mc (34)
polyclonal pc (78)
recombinant monoclonal rmc (2)
1022-5 (3)
2A2-B6 (1)
5G4E7 (1)
AIF1/1909 (2)
AIF1/2493 (2)
GF1 (1)
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aa1-147 (42)
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aa138-148 (1)
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No (113)
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AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
AIF1 / IBA1 Goat anti-Human Polyclonal (aa42-56) Antibody
Dog, Pig, Horse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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AIF1 / IBA1 Goat anti-Human Polyclonal (aa149-161) Antibody
Mouse, Rat, Hamster, Pig, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIF1 / IBA1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
AIF1 / IBA1 Rabbit anti-Rat Polyclonal (aa1-147) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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AIF1 / IBA1 Goat anti-Human Polyclonal (aa138-148) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
AIF1 / IBA1 Antibody - Immunohistochemistry of paraffin-embedded mouse lung using AIF1 antibodyat dilution of 1:100 (40x lens).
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AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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AIF1 / IBA1 Mouse anti-Human Monoclonal (Biotin) (1022-5) Antibody
Rat, Human
IHC, IHC-P
Biotin Conjugated
100 µg/$575
AIF1 / IBA1 Antibody - Biotinylated Goat Anti-AIF1 / IBA1 (isoform 1 and 3) Antibody (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.
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AIF1 / IBA1 Goat anti-Human Polyclonal (Biotin) Antibody
Human
Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
AIF1 / IBA1 Antibody - IHC of AIF1 / IBA1 antibody. Formalin-fixed, paraffin-embedded human spleen.
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AIF1 / IBA1 Mouse anti-Human Monoclonal (1022-5) Antibody
Rat, Human
IHC, IHC-P
Unconjugated
200 µg/$850
AIF1 / IBA1 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa6-36) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa6-36) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa6-36) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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AIF1 / IBA1 Mouse anti-Human Monoclonal (GF1) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$872
AIF1 / IBA1 Antibody - AIF1 monoclonal antibody (M01), clone 2A2-B6 Western Blot analysis of AIF1 expression in K-562.
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AIF1 / IBA1 Mouse anti-Human Monoclonal (2A2-B6) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Neuroscience
AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa85-147) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
AIF1 / IBA1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
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AIF1 / IBA1 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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AIF1 / IBA1 Mouse anti-Human Monoclonal (FITC) (1022-5) Antibody
Rat, Human
IHC
FITC Conjugated
200 µg/$850
AIF1 / IBA1 Antibody - Western blot of AIF1 / IBA1 antibody.
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AIF1 / IBA1 Rabbit anti-Guinea pig Polyclonal (aa1-147) Antibody
Guinea pig
WB
Unconjugated
100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401
AIF1 / IBA1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
AIF1 / IBA1 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using AIF1 Polyclonal Antibody at dilution of 1:40.
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AIF1 / IBA1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AIF1 / IBA1 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) HIER using 10 mM sodium citrate buffer pH 6.0
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Fast Shipping
AIF1 / IBA1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
IHC-P
Unconjugated
50 µg/$460
AIF1 / IBA1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) HIER using 10 mM sodium citrate buffer pH 6.0
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Fast Shipping
AIF1 / IBA1 Rabbit anti-Human Polyclonal (N-Terminal) Antibody
IHC-P
Unconjugated
50 µg/$460
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).