AIMP1 / EMAP II

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

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Products

Proteins (14)

Type

Over-Expression Lysate (6)

Recombinant (8)

Target

AIMP1 / EMAP II (14)

Publications

No (14)

Tag

6His-SUMO, N-terminus (1)

GST (1)

His (2)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (9)

Mouse (2)

Source

293T Cells (3)

E. coli (7)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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Human AIMP1 / EMAP II Protein (Recombinant) - LS-G131231

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~18 kDa

Price:

20 µg/$432; 1 mg/$6,427

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Human AIMP1 / EMAP II Protein (Recombinant His) - LS-G1078

Source:

E. coli

Tag:

His

Price:

10 µg/$361; 50 µg/$739

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Human AIMP1 / EMAP II Protein (Recombinant) (aa147-312) - LS-G5772

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.2 kDa

Price:

5 µg/$282; 100 µg/$1,197; 500 µg/$2,293

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Human AIMP1 / EMAP II Protein (Recombinant His) (aa148-312) - LS-G16165

Source:

E. coli

Tag:

His

Molecular Weight:

19.6 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human AIMP1 / EMAP II Protein (Recombinant GST) (Full Length) - LS-G31553

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

60.06 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AIMP1 / EMAP II Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81438

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

20 µg/$150

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Human AIMP1 / EMAP II Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81439

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.35 kDa

Price:

20 µg/$150

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Human AIMP1 / EMAP II Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81440

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

20 µg/$150

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AIMP1 / EMAP II Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125914

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

100 µg/$494

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AIMP1 / EMAP II Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125915

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.35 kDa

Price:

100 µg/$494

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AIMP1 / EMAP II Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116432

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.2 kDa

Price:

100 µg/$494

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Human AIMP1 / EMAP II Protein (Recombinant His, N-Terminal) - LS-G144570

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

34.2 kDa

Price:

50 µg/$419

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Mouse AIMP1 / EMAP II Protein (Recombinant His-T7) (aa2-310) - LS-G26138

Source:

E. coli

Tag:

His-T7

Molecular Weight:

37.6 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Mouse AIMP1 / EMAP II Protein (Recombinant 6His-SUMO, N-terminus) (aa2-310) - LS-G56514

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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