AKAP10

A kinase (PRKA) anchor protein 10

Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase.

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Proteins (2)

Type

Recombinant (2)

Target

AKAP10 (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human AKAP10 Protein (Recombinant GST) (Full Length) - LS-G32563

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

100.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AKAP10 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G61788

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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