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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function.
Gene Name: | A kinase (PRKA) anchor protein 11 |
Synonyms: | AKAP11, A-kinase anchor protein 11, AKAP-11, AKAP 220, AKAP220, HAKAP220, KIAA0629, PPP1R44, PRKA11 |
Target Sequences: | NM_016248 NP_057332.1 Q9UKA4 |
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