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AKAP8 / AKAP95 is a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
Gene Name: | A kinase (PRKA) anchor protein 8 |
Synonyms: | AKAP8, A-kinase anchor protein 8, A-kinase anchor protein, 95kDa, A-kinase anchor protein 95 kDa, AKAP-8, AKAP95, AKAP 95, AKAP-95 |
Target Sequences: | NM_005858 NP_005849.1 O43823 |
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