ALDH18A1

aldehyde dehydrogenase 18 family, member A1

ALDH18A1 is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

ALDH18A1 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ALDH18A1 Protein (Recombinant GST) (Full Length) - LS-G30061

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

113.9 kDa

Price:

2 µg/$439

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Human ALDH18A1 Protein (Recombinant GST, N-terminus) (aa696-795) - LS-G59841

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ALDH18A1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65380

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.1 kDa

Price:

20 µg/$1,107

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Human ALDH18A1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75465

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.1 kDa

Price:

20 µg/$150

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ALDH18A1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117707

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.1 kDa

Price:

100 µg/$494

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