ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

ALDH2 (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-S (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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Human ALDH2 Protein (Recombinant) - LS-G486

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$317; 500 µg/$526; 20 µg/$245

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Mouse ALDH2 Protein (Recombinant His) - LS-G3318

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Human ALDH2 Protein (Recombinant His-S) (aa59-150) - LS-G14643

Source:

E. coli

Tag:

His-S

Molecular Weight:

16.1 kDa

Price:

10 µg/$246; 50 µg/$299; 100 µg/$352; 200 µg/$442; 1 mg/$1,242; 500 µg/$882; 5 mg/$2,097; 2 mg/$1,391

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Human ALDH2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64883

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.4 kDa

Price:

20 µg/$1,107

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Human ALDH2 Protein (Recombinant GST, N-terminus) (aa408-517) - LS-G57746

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ALDH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99116

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.38 kDa

Price:

100 µg/$494

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Human ALDH2 Protein (Recombinant His, N-Terminal) (Ser18-Ser517) - LS-G96747

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

57 kDa

Price:

10 µg/$265; 100 µg/$365; 250 µg/$518; 50 µg/$315

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Human ALDH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74399

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.38 kDa

Price:

20 µg/$150

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Human ALDH2 Protein (Recombinant GST) (Full Length) - LS-G27415

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

82.8 kDa

Price:

10 µg/$479; 25 µg/$670

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