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ALKBH1 / ALKB

alkB, alkylation repair homolog 1 (E. coli)

Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.

Gene Name: alkB, alkylation repair homolog 1 (E. coli)
Synonyms: ALKBH1, ABH, ABH1, ALKBH, Alkb protein homolog, HABH, AlkB, DNA lyase ABH1
Target Sequences: NM_006020 NP_006011.2 Q13686

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
ALKBH1 / ALKB (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
ALKBH1 / ALKB Protein - 12.5% SDS-PAGE of human ALKBH stained with Coomassie Blue
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Wheat Germ Extract
GST
68.42 kDa
10 µg/$479; 25 µg/$670
ALKBH1 / ALKB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43.7 kDa
20 µg/$150
ALKBH1 / ALKB Protein - Purified recombinant protein ALKBH1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
43.7 kDa
20 µg/$1,107
ALKBH1 / ALKB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
43.7 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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Products: Proteins


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).