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ALKBH7

AlkB, Alkylation Repair Homolog 7 (E. Coli)

Probable dioxygenase required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism.

Gene Name: AlkB, Alkylation Repair Homolog 7 (E. Coli)
Synonyms: ALKBH7, ABH7, SPATA11, UNQ6002, Spermatogenesis associated 11
Target Sequences: NM_032306 NP_115682.1 Q9BT30

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
ALKBH7 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
ALKBH7 Protein - 12.5% SDS-PAGE of human ALKBH7 stained with Coomassie Blue
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Wheat Germ Extract
GST
50.9 kDa
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
24.3 kDa
20 µg/$150
ALKBH7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.3 kDa
100 µg/$494
ALKBH7 Protein - Purified recombinant protein ALKBH7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.3 kDa
20 µg/$1,107
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).