ALPL / Alkaline Phosphatase

alkaline phosphatase, liver/bone/kidney

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.

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Products

Proteins (17)

Type

Over-Expression Lysate (6)

Recombinant (11)

Target

ALPL / Alkaline Phosphatase (17)

Publications

No (17)

Tag

6His, C-terminus (2)

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (4)

His-T7 (1)

Myc-DDK (Flag) (7)

Species

Human (11)

Mouse (2)

Rat (1)

Source

293T Cells (3)

E. coli (5)

HEK 293 Cells (4)

Human Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (4)

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Rat ALPL / Alkaline Phosphatase Protein (Recombinant 6His-SUMO, N-terminus) (aa18-501) - LS-G56086

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human ALPL / Alkaline Phosphatase Protein (Recombinant His-T7) (aa18-335) - LS-G13347

Source:

E. coli

Tag:

His-T7

Molecular Weight:

39.5 kDa

Price:

50 µg/$422; 10 µg/$278; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse ALPL / Alkaline Phosphatase Protein (Recombinant His) (aa18-335) - LS-G13346

Source:

E. coli

Tag:

His

Molecular Weight:

37.2 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human ALPL / Alkaline Phosphatase Protein (Recombinant 6His, C-terminus) (Leu18-Ser502) - LS-G39057

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54.5kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human ALPL / Alkaline Phosphatase Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64888

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

55.5 kDa

Price:

20 µg/$1,107

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Human ALPL / Alkaline Phosphatase Protein (Recombinant GST, N-terminus) (aa91-200) - LS-G57755

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ALPL / Alkaline Phosphatase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99050

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

100 µg/$494

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Human ALPL / Alkaline Phosphatase Protein (Recombinant His) (Met1-Ser502) - LS-G97156

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

55 kDa

Price:

50 µg/$854

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Human ALPL / Alkaline Phosphatase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74404

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

20 µg/$150

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Human ALPL / Alkaline Phosphatase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74405

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

20 µg/$150

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Human ALPL / Alkaline Phosphatase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74406

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.4 kDa

Price:

20 µg/$150

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ALPL / Alkaline Phosphatase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124653

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

57.3 kDa

Price:

100 µg/$494

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ALPL / Alkaline Phosphatase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129837

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.4 kDa

Price:

100 µg/$494

Select

Human ALPL / Alkaline Phosphatase Protein (Recombinant 6His, C-terminus) (Leu18-Ser502) - LS-G140038

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54.5 kDa

Price:

10 µg/$344; 50 µg/$584

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Human ALPL / Alkaline Phosphatase Protein (Recombinant His) (aa80-205) - LS-G141017

Source:

E. coli

Sequence Length:

125 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

13.86 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human ALPL / Alkaline Phosphatase Protein (Recombinant GST) (Full Length) - LS-G27434

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse ALPL / Alkaline Phosphatase Protein (Recombinant His) (aa20-503) - LS-G22715

Source:

E. coli

Tag:

His

Molecular Weight:

57.5 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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