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May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.
Gene Name: | hematopoietic SH2 domain containing |
Synonyms: | HSH2D, ALX, Hematopoietic SH2 protein, HSH2 |
Target Sequences: | NM_032855 NP_116244.1 Q96JZ2 |
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