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AMACR / P504S

alpha-methylacyl-CoA racemase

AMACR / P504S is a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Gene Name: alpha-methylacyl-CoA racemase
Synonyms: AMACR, 2-methylacyl-CoA racemase, AMACRD, Alpha-methylacyl-CoA racemase, CBAS4, RACE, RM, AMACR/p504S
Target Sequences: NM_014324 NP_055139.4 Q9UHK6

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Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
AMACR / P504S (10)
No (10)
GST (1)
His, N-Terminal (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (7)
Human (7)
293T Cells (3)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
AMACR / P504S Protein - 12.5% SDS-PAGE of human AMACR stained with Coomassie Blue
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Wheat Germ Extract
GST
47.52 kDa
2 µg/$439
AMACR / P504S Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
44.3 kDa
20 µg/$150
AMACR / P504S Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
42.2 kDa
20 µg/$150
AMACR / P504S Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
22 kDa
20 µg/$150
AMACR / P504S Protein
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E. coli
His, N-Terminal
24 kDa
10 µg/$265; 100 µg/$365; 50 µg/$315
AMACR / P504S Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.2 kDa
100 µg/$494
AMACR / P504S Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
100 µg/$494
AMACR / P504S Protein - Purified recombinant protein AMACR was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.2 kDa
20 µg/$1,107
AMACR / P504S Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
44.3 kDa
100 µg/$494
AMACR / P504S Protein - Recombinant Alpha-Methylacyl Coenzyme A Racemase (aMACR) by SDS-PAGE
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E. coli
His-T7, N-terminus
19.7kDa
10 µg/$290; 50 µg/$500; 200 µg/$997; 100 µg/$797; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).