AMICA / JAML

adhesion molecule, interacts with CXADR antigen 1

Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

AMICA / JAML (7)

Publications

No (7)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Human Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human AMICA / JAML Protein (Recombinant GST) (Full Length) - LS-G36313

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AMICA / JAML Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93109

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

20 µg/$150

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Human AMICA / JAML Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93110

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.9 kDa

Price:

20 µg/$150

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AMICA / JAML Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105867

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.9 kDa

Price:

100 µg/$494

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Human AMICA / JAML Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72634

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

20 µg/$1,107

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AMICA / JAML Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119252

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.2 kDa

Price:

100 µg/$494

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Human AMICA / JAML Protein (Recombinant His) (Met1-Leu275) - LS-G98609

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

30.5 kDa

Price:

100 µg/$721

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