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ANGPTL4

angiopoietin-like 4

Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Gene Name: angiopoietin-like 4
Synonyms: ANGPTL4, Angiopoietin-like 4, Angiopoietin-related protein 4, Angiopoietin-like protein 4, Fasting-induced adipose factor, NL2, PGAR, Pp1158, ARP4, FIAF, HFARP
Target Sequences: AF202636 AAG22490.1 Q9BY76

Publications (1)

1
ANGPTL4 Promotes the Proliferation of Papillary Thyroid Cancer via AKT Pathway. Longyan Yang , Yan Wang , Rongxin Sun , Yuanyuan Zhang, Ying Fu, Zhaohui Zheng, Zhili Ji, Dong Zhao. OncoTargets and therapy. 2020 Mar;13:2299-2309. [Full Text Article] [PubMed:32231436] [PMC:PMC7085330] Related Antibodies: LS-C331822.

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Antibodies (93)
Primary (93)
ANGPTL4 (93)
Human (41)
Mouse (26)
Rat (29)
Bovine (8)
Cow (8)
Monkey (1)
Pig (8)
IHC (9)
IHC-P (7)
WB (88)
Flo (1)
ELISA (22)
ICC (8)
IF (4)
IP (10)
Peptide-ELISA (1)
rabbit (80)
mouse (12)
sheep (1)
Product Group
IHCPlus (1)
IgG (29)
IgG1,k (3)
monoclonal mc (11)
polyclonal pc (82)
1A12 (1)
Kairos-1 (1)
Kairos4-397G (1)
APC (7)
APC Conjugated (8)
Biotin Conjugated (8)
Cy3 Conjugated (7)
Cy7 Conjugated (7)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (8)
Preservative Free (2)
Unconjugated (39)
aa182-394 (16)
aa182-388 (8)
aa183-401 (8)
aa227-389 (8)
aa228-389 (8)
aa286-409 (8)
Coiled-coil domain (2)
aa26-406 (2)
301-350 aa, Internal (1)
Fibrinogen-like domain (1)
Internal (1)
N-Terminus (1)
aa138-167 (1)
aa251-406 (1)
aa349-367 (1)
aa79-101 (1)
aa81-94 (1)
No (92)
Yes (1)
ANGPTL4 Antibody - Immunohistochemistry of paraffin-embedded rat lung using ANGPTL4 antibody at dilution of 1:100 (200x lens).
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ANGPTL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ANGPTL4 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ANGPTL4 Mouse anti-Human Monoclonal (Coiled-coil domain) (Kairos4-397G) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ANGPTL4 Antibody - Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ANGPTL4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ANGPTL4 Rabbit anti-Human Polyclonal (aa138-167) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ANGPTL4 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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ANGPTL4 Rabbit anti-Human Polyclonal (aa26-406) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ANGPTL4 Antibody - Immunohistochemical staining of human tissue using anti-ANGPTL4 (human), mAb (Kairos-1) at 1:500 dilution. A. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human spleen (200x). A-1. Isotype control (negative control). B. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver (200x). .B-1. Isotype control (negative control).
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ANGPTL4 Mouse anti-Human Monoclonal (Kairos-1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$365; 100 µg/$421
ANGPTL4 Antibody
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ANGPTL4 Rabbit anti-Human Polyclonal (aa251-406) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
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ANGPTL4 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
0.1 mg/$379
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ANGPTL4 Rabbit anti-Human Polyclonal (aa81-94) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$657
ANGPTL4 Antibody - Immunoprecipitation of ANGPTL4 transfected lysate using anti-ANGPTL4 monoclonal antibody and Protein A Magnetic Bead.
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ANGPTL4 Mouse anti-Human Monoclonal (1A12) Antibody
Human
ELISA, IP
Unconjugated
100 µg/$423
ANGPTL4 Antibody - Western blot analysis using anti-ANGPTL4 (human), pAb at 1:2000 dilution. 1: Human ANGPTL1 (FLAG-tagged). 2: Human ANGPTL2 (FLAG-tagged). 3: Human ANGPTL3 (FLAG-tagged). 4: Human ANGPTL4 (FLD) (FLAG-tagged). 5: Human ANGPTL4 (CCD) (FLAG-tagged). 6: Human ANGPTL6 (FLAG-tagged). 7: Human ANGPTL7 (FLAG-tagged). 7: Mouse RBP4 (FLAG-tagged) (negative control).
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ANGPTL4 Rabbit anti-Human Polyclonal (aa79-101) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$407
ANGPTL4 Antibody - Western blot analysis using anti-ANGPTL4 (CCD) (human), pAb at 1:2000 dilution. 1: Human ANGPTL4 (CDD) (FLAG-tagged). 2: Human ANGPTL4 (FLAG-tagged). 3: Human ANGPTL3 (CCD) (FLAG-tagged). 4: Human ANGPTL3 (FLAG-tagged). 5: Human ANGPTL3 (FLD) (FLAG-tagged). 6: Human ANGPTL2 (CCD) (FLAG-tagged). 7: Human ANGPTL5 (CCD) (FLAG-tagged).
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ANGPTL4 Rabbit anti-Human Polyclonal (Coiled-coil domain) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$407
ANGPTL4 Antibody - Western blot analysis using anti-ANGPTL4 (FLD) (human), pAb at 1:2000 dilution. A). 1: Human ANGPTL4 (FLD) (FLAG-tagged). 2: Human ANGPTL4 (FLAG-tagged). 3: Human ANGPTL4 (CCD) (FLAG-tagged). 4: Human ST2 (FLAG-tagged) (negative control). B). 1: Human ANGPTL3 (FLD) (FLAG-tagged). 2: Human ANGPTL3 (FLAG-tagged). 3: Human ANGPTL6 (FLAG-tagged). 4: Human ANGPTL6 (FLD) (FLAG-tagged). 5: Human ANGPTL5 (FLD) (FLAG-tagged).
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ANGPTL4 Rabbit anti-Human Polyclonal (Fibrinogen-like domain) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$400
ANGPTL4 Antibody - anti-ANGPTL4 antibody, Western blotting All lanes: Anti ANGPTL4 at 0.5ug/ml Lane 1: Human Placenta Tissue Lysate at 50ugLane 2: SMMC Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 50KD Observed bind size: 50KD
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ANGPTL4 Rabbit anti-Human Polyclonal (aa349-367) Antibody
Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
ANGPTL4 Antibody - Western blot of recombinant ANGPTL4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ANGPTL4 Rabbit anti-Human Polyclonal (aa182-388) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
ANGPTL4 Antibody - Anti-ANGPTL4 rabbit polyclonal antibody at 1:500 dilution. Lane A: Mouse liver tissue lysate. Lane B: Mouse skeletal muscle tissue lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H&L) /Dylight 800 at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 45 kDa. Observed band size: 54 kDa.
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ANGPTL4 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ELISA, IHC-P, WB
Unconjugated, Preservative Free
100 µl/$412
ANGPTL4 Antibody - Western Blot; Sample: Recombinant ANGPTL4, Porcine.
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ANGPTL4 Rabbit anti-Pig Polyclonal (aa227-389) Antibody
Pig
WB
Unconjugated
100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401
ANGPTL4 Antibody - Western blot of Angptl4 antibody
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ANGPTL4 Rabbit anti-Human Polyclonal (301-350 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ANGPTL4 Antibody - Western blot analysis of lysate from MCF7 cells, using ANGPTL4 Antibody.
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ANGPTL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ANGPTL4 Antibody - Western blot of recombinant ANGPTL4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ANGPTL4 Rabbit anti-Mouse Polyclonal (aa183-401) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ANGPTL4 Antibody - Western blot of recombinant ANGPTL4. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ANGPTL4 Rabbit anti-Mouse Polyclonal (aa183-401) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
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ANGPTL4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
ANGPTL4 Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle using antibody at 1:100 dilution.
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ANGPTL4 Rabbit anti-Human Polyclonal (aa26-406) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
ANGPTL4 Antibody - 1:100 staining human lung carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ANGPTL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ANGPTL4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
ANGPTL4 Antibody - Western blot of recombinant ANGPTL4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ANGPTL4 Mouse anti-Rat Monoclonal (aa182-394) Antibody
Rat
ICC, IP, WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$516; 1 ml/$593
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).