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ANK2 / Ankyrin B

ankyrin 2, neuronal

In skeletal muscle, required for proper localization of DMD and DCTN4 and for the formation and/or stability of a special subset of microtubules associated with costameres and neuromuscular junctions (By similarity). Attaches integral membrane proteins to cytoskeletal elements. Also binds to cytoskeletal proteins. Required for coordinate assembly of Na/Ca exchanger, Na/K ATPase and InsP3 receptor at sarcoplasmic reticulum sites in cardiomyocytes. Required for the coordinated expression of the Na/K ATPase, Na/Ca exchanger and beta-2-spectrin (SPTBN1) in the inner segment of rod photoreceptors. Required for expression and targeting of SPTBN1 in neonatal cardiomyocytes and for the regulation of neonatal cardiomyocyte contraction rate.

Gene Name: ankyrin 2, neuronal
Synonyms: ANK2, Ankyrin 2, neuronal, Ankyrin, brain, Ankyrin, brain variant 2, ANK-2, Ankyrin B, Ankyrin-2, Ankyrin-2, nonerythrocytic, Ankyrin-B, Brain ankyrin, Brank-2, LQT4, Non-erythroid ankyrin
Target Sequences: NM_001148 NP_001139.3 Q01484

Publications (1)

1
Polarization of membrane associated proteins in the choroid plexus epithelium from normal and slc4a10 knockout mice. Christensen IB, Gyldenholm T, Damkier HH, Praetorius J. Frontiers in physiology. 2013 4:344. (IHC; Mouse) [Full Text Article] [PubMed:24348423] [PMC:PMC3842056]

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ANK2 / Ankyrin B (5)
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ANK2 / Ankyrin B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ANK2 / Ankyrin B ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$669
ANK2 / Ankyrin B ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
ANK2 / Ankyrin B ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
ANK2 / Ankyrin B ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).